IMMUNOREL 100ML

Clinical conditions where Human Immunoglobulin is indicated as under: Primary Immunodeficiency (PID), β-cell Chronic lymphocytic leukemia, Kawasaki Syndrome, Pediatric HIV-1 infection, Idiopathic Thrombocytopenic Purpura (ITP) and Hemopoietic stem cell transplantation in elderly.

SKU: IMMUNOREL 5% 50mg/ml VIAL 100ml 1
MOLECULE: Immunoglobulin
THERAPEUTIC CLASS: IMMUNOLOGY

FORMULATION:
Each mL contains:
Protein Content…50mg/mL
Immunoglobulin G…≥ 95%
Stabilizer Maltose…100mg/mL
IgA content…≤0.08 mg/mL

DOSAGE AND ADMINISTRATION:

Doses and Frequency must be based primarily on clinical course and response:

For Replacement therapy in PID: Starting dose is 0.4-0.8 g/kg followed by 0.2-0.8 g/kg every 2-4 weeks to obtain IgG through level of at least 4-6 g/L.

For Replacement therapy in secondary immunodeficiency: 0.2-0.4 g/kg every 3-4 week to obtain IgG trough level of at least 4-6 g/L.

For Allogeneic Bone Marrow Transplantation 9BMT):
1. Treatment of infections & prophylaxis of graft versus host disease: 0.5 g/kg every week from day 7 up to 3 months after transplantation;
2. Persistent lack of Ab production: 0.5 g/kg every month until Ab levels return to normal.

For ITP: 0.8-1 g/kg on day 1 repeated once within 3 days or 0.4 g/kg/day for 2-5 days.

For Kawasaki disease: 1.6-2 g/kg in several doses for 2-5 days or 2 g/kg as a single dose w/ acetylsalicylic acid.

For Ped HIV :0.2-0.4 g/kg every 3-4 weeks.

For Guillain-Barre syndrome (GBS): 0.4 g/kg/day for 3-7 days.